Education & Academic Appointments

• Faculty Member, Department of Medical Physics, Memorial Sloan Kettering Cancer Center (2015-present)

• Postdoc Fellow, School of Medicine & Department of Management Science and Engineering, Stanford (2013-2015)

  • Supervisors: Lei Xing, Yinyu Ye

• Postdoc Fellow, Department of Radiation Medicine and Applied Sciences, University of California, San Diego (2011-2013)

  • Superviso: Steve B. Jiang

• Ph.D., Applied Mathematics (Operations Research) (2006-2011) [Thesis]

  • Department of Industrial and Systems Engineering, University of Florida

  • Department of Mathematics and Computer Science, Amirkabir University of Technology,Tehran, Iran

  • Supervisors: Panos M. Pardalos, Esmaile Khorram

Honors & Awards

• (2021) Franz Edelman Finalist, The Institute for Operations Research and Management Science (INFORMS)

• (2019) Clinical Service Award, Department of Medical Physics, Memorial Sloan Kettering Cancer Center

• (2012) Best Paper Award, Norm Baily, American Association of Physicists in Medicine (AAPM), Southern California Chapter

• (2003) Ranked First, Nationwide M.Sc. entrance exam in Applied Mathematics of Iranian Universities

• (2003) Ranked Third, Nationwide M.Sc. entrance exam in Systems and Industrial Engineering of Iranian Universities

Publications

2024

• Simultaneous reduction of number of spots and energy layers in intensity modulated proton therapy for rapid spot scanning delivery
  | arXiv |
  Anqi Fu, Vicki T. Taasti, Masoud Zarepisheh
  Medical Physics

• Automated planning of stereotactic spine re-irradiation using cumulative dose limits
  Sebastian Meyer, Lei Zhang, Yilin Liu, Li Cheng Kuo, Yu-Chi Hu, Yoshiya Yamada, Masoud Zarepisheh, Pengpeng Zhang, Laura Cerviño
  Physics and Imaging in Radiation Oncology

2023

• Automated VMAT treatment planning using sequential convex programming: algorithm development and clinical implementation
  | Code |
  Pınar Dursun, Linda Hong, Gourav Jhanwar, Qijie Huang, Ying Zhou, Jie Yang, Hai Pham, Laura Cervino, Jean M Moran, Joseph O Deasy, Masoud Zarepisheh
  Physics in Medicine & Biology

• Built-in wavelet-induced smoothness to reduce plan complexity in intensity modulated radiation therapy (IMRT)
  | Code |
  Mojtaba Tefagh, Masoud Zarepisheh
  Physics in Medicine & Biology

• RMSim: controlled respiratory motion simulation on static patient scans
  | arXiv | Code |
  Donghoon Lee, Ellen Yorke, Masoud Zarepisheh, Saad Nadeem, Yu-Chi Hu
  Physics in Medicine & Biology

2022

• Distributed and scalable optimization for robust proton treatment planning
  | Slides |
  Anqi Fu, Vicki T. Taasti, Masoud Zarepisheh
  Medical Physics

• Domain knowledge driven 3D dose prediction using moment-based loss function
  | arXiv | Code |
  G Jhanwar, N Dahiya, P Ghahremani, Masoud Zarepisheh, S Nadeem
  Physics in Medicine & Biology

• Automated and Clinically Optimal Treatment Planning for Cancer Radiotherapy
  | YouTube | Slides | Podcast | Edelman Competition |
  Masoud Zarepisheh, Linda Hong, Ying Zhou, Qijie Huang, Jie Yang, Gourav Jhanwar, Hai D. Pham, Pınar Dursun, Pengpeng Zhang, Margie A. Hunt, Gig S. Mageras, Jonathan T. Yang, Yoshiya (Josh) Yamada, Joseph O. Deasy
  INFORMS Journal on Applied Analytics

2021

• Solving the volumetric modulated arc therapy (VMAT) problem using a sequential convex programming method
  Pınar Dursun, Masoud Zarepisheh, Gourav Jhanwar and Joseph O Deasy
  Physics in Medicine and Biology

• Methods and systems for automatic radiotherapy treatment planning
  Masoud Zarepisheh, JO Deasy, L Hong, GS Mageras, JG Mechalakos
  US Patent App. 16/978,397

• Deep learning auto-segmentation and automated treatment planning for trismus risk reduction in head and neck cancer radiotherapy
  Maria Thor, Aditi Iyer, Jue Jiang, Aditya Apte, Harini Veeraraghavan, Natasha B Allgood, Jennifer A Kouri, Ying Zhou, Eve LoCastro, Sharif Elguindi, Linda Hong, Margie Hunt, Laura Cerviño, Michalis Aristophanous, Masoud Zarepisheh, Joseph O Deasy
  Physics and imaging in radiation oncology

2020

• Automating Proton Treatment Planning with Beam Angle Selection Using Bayesian Optimization
  | Slides |
  Vicki T. Taasti, Linda Hong, Jin Sup(Andy) Shim, Joseph O. Deasy, and Masoud Zarepisheh
  Medical Physics

• Automated Proton Treatment Planning with Robust Optimization Using Constrained Hierarchical Optimization
  | Slides |
  Vicki T. Taasti, Linda Hong, Joseph O. Deasy, and Masoud Zarepisheh
  Medical Physics

• Integrating Soft and Hard Dose-Volume Constraints into Hierarchical Constrained IMRT Optimization
  | Slides |
  Sovanlal Mukherjee, Linda Hong, Joseph O. Deasy, and Masoud Zarepisheh
  Medical Physics

• Clinical Experience of Automated SBRT Paraspinal and Other Metastatic Tumor Planning With Constrained Hierarchical Optimization
  Hong, Linda, Ying Zhou, Jie Yang, James G. Mechalakos, Margie A. Hunt, Gig S. Mageras, Jonathan Yang, Josh Yamada, Joseph O. Deasy, and Masoud Zarepisheh
  Advances in Radiation Oncology

2019

• Automated Intensity Modulated Treatment Planning: The Expedited Constrained Hierarchical Optimization (ECHO) System
  Masoud Zarepisheh, Linda Hong, Ying Zhou, Jung Hun Oh, James G. Mechalakos, Margie A. Hunt, Gig S. Mageras, and Joseph O. Deasy
  Medical Physics

• Inverse optimization for multi-objective linear programming
  | Slides |
  Mostafa Naghavi, Ali Asghar Foroughi, Masoud Zarepisheh
  Optimization Letters

2018

• Advances in Inverse Planning Algorithm and Strategy
  Masoud Zarepisheh, B Ungun, R Li, Y Ye, S Boyd, L Xing
  (Book Chapter) Advanced and Emerging Technologies in Radiation Oncology Physics

• A computation study on an integrated alternating direction method of multipliers for large scale optimization
  | Slides |
  Masoud Zarepisheh, L Xing, Y Ye
  Optimization Letters

2017

• An equivalent transformation of multi-objective optimization problems
  Masoud Zarepisheh and P M Pardalos
  Annals of Operations Research

2016

• An Automated Treatment Plan Quality Control Tool for Intensity-Modulated Radiation Therapy Using a Voxel-Weighting Factor-Based Re-Optimization Algorithm
  T Song, N Li, M Zarepisheh, Y Li, Q Gautier, L Zhou, L Mell, S Jiang, L Cerviño
  PlOS one

• SCORE System for Online Adaptive Radiotherapy
  Z Tian, Q Gautier, X Gu, C Men, F Peng, M Zarepisheh, Y Graves, A Uribe, X Jia, S B Jiang
  (Book Chapter) Graphics Processing Unit-Based High Performance Computing in Radiation Therapy

2015

• Dosimetric benefit of adaptive re-planning in pancreatic cancer stereotactic body radiotherapy
  Y Li, J Hoisak, N Li, C Jiang, Z Tian, Q Gautier, M, Z Wu, Y Liu, X Jia, J Hattangadi-Gluth, L K Mell, S Jiang, J D Murphy
  Medical Dosimetry

• Simultaneous beam sampling and aperture shape optimization for station parameter optimized radiation therapy (SPORT)
  Masoud Zarepisheh, R Li, Y Ye, and L Xing
  Medical Physics

2014

• A DVH-guided IMRT optimization algorithm for automatic treatment planning and adaptive radiotherapy re-planning
  Masoud Zarepisheh, T Long, N Li, Z Tian, HE Romeijn, X Jia, SB Jiang
  Medical physics

• A multicriteria framework with voxel-dependent parameters for radiotherapy treatment plan optimization
  Masoud Zarepisheh, AF Uribe-Sanchez, N Li, X Jia, and SB Jiang
  Medical physics

• The nearest MPSS pattern in data envelopment analysis
  A Davoodi, Masoud Zarepisheh, HZ Rezai
  Annals of Operations Research

2013

• Automatic treatment plan re-optimization for adaptive radiotherapy guided with the initial plan DVHs
  N Li, M Zarepisheh, A Uribe, K Moore, Z Tian, X Zhen, Y Graves1, Q Gautier1, L Mell, L Zhou
  Physics in Medicine and Biology

• A moment-based approach for DVH-guided radiotherapy treatment plan optimization
  M Zarepisheh, M Shakourifar, G Trigila, P S Ghomi, S Couzens, A Abebe, L Noreña, W Shang, S Jiang and Y Zinchenko
  Physics in Medicine and Biology

2012 (and before)

• A linear bi-level programming problem for obtaining the closest targets and minimum distance of a unit from the strong efficient frontier
  GR Jahanshahloo, J Vakili, Masoud Zarepisheh
  Asia-Pacific Journal of Operational Research

• Generating properly efficient points in multi-objective programs by the nonlinear weighted sum scalarization method
  Masoud Zarepisheh, E Khorram, and P M Pardalos
  Optimization

• On the transformation of lexicographic nonlinear multiobjective programs to single objective programs
  Masoud Zarepisheh, and E Khorram
  Mathematical Methods of Operations Research (2011)

• Sensitivity analysis on the priority of the objective functions in lexicographic multiple objective linear programs
  E Khorram, M Zarepisheh, BA Ghaznavi-ghosoni
  European Journal of Operational Research (2010)

• Returns to scale in multiplicative models in data envelopment analysis
  Masoud Zarepisheh, E Khorram, GR Jahanshahloo
  Annals of Operations Research (2010)

• Preemptive priority based algorithms for fuzzy minimal cost flow problem: An application in hazardous materials transportation
  M Ghatee, S Mehdi Hashemi, M Zarepisheh, E Khorram
  Computers & Industrial Engineering (2009)

• Linear transformations to decrease computational requirements of solving some known linear programming models
  M Zarepisheh, M Soleimani-damaneh
  Annals of Operations Research (2009)

• A dual simplex-based method for determination of the right and left returns to scale in DEA
  M Zarepisheh, M Soleimani-damaneh
  European Journal of Operational Research (2009)

• Shannon’s entropy for combining the efficiency results of different DEA models: method and application
  M Soleimani-damaneh, M Zarepisheh
  Expert Systems with Applications (2009)

• Global variation of outputs with respect to the variation of inputs in performance analysis; generalized RTS
  M Zarepisheh, M Soleimani-damaneh
  European Journal of Operational Research (2008)

• A dual-based algorithm for solving lexicographic multiple objective programs
  L Pourkarimi, and M Zarepisheh
  European Journal of Operational Research (2007)

• Determination of returns to scale by CCR formulation without chasing down alternative optimal solutions
  M Zarepisheh, M Soleimani-damaneh, L Pourkarimi
  Applied Mathematics Letters (2006)

• Modified MAJ model for ranking decision making units in data envelopment analysis
  GR Jahanshahloo, L Pourkarimi, M Zarepisheh
  Applied Mathematics and Computation (2006)